The Church of San Lorenzo in Manarola, actually dedicated to the Nativity of the Virgin Mary, was built in 1338 and is traditionally attributed to the Antelami Masters. The building has an elegant Gothic style, particularly evident in the façade, characterised by a portal surmounted by an arch and a lunette decorated with a bas-relief depicting San Lorenzo, patron saint of the village.

Of particular value is the large central rose window, composed of twelve slender columns with capitals decorated with leaves and enclosed by a frame adorned with sculpted heads of men and lions, which give the façade a strong symbolic and artistic value.

Inside, the church is divided into three naves and features Baroque decorative elements introduced in subsequent centuries. Among the most significant works is the triptych depicting the Madonna and Child flanked by St. Lawrence and St. Catherine.